Enhancing the Thermal Stability of Sucrose Phosphorylase from Streptococcus mutans by Random Mutagenesis

The Comparison of Proteins Elaborated by Streptococcus mutans Strains Isolated from Caries Free and Susceptible Subjects

Preferential utilization of the glucosyl moiety of sucrose by a cariogenic strain of Streptococcus mutans.

The utilization of sucrose by a cariogenic strain of Streptococcus mutans was studied. The soluble and cell-bound sucrose-dependent, polymer-forming sucrase activities constitutively produced by the bacteria during growth on glucose were measured. About eight times more dextransucrase activity was present than levan-sucrase activity. During various states of growth on sucrose, S. mutans accumul...

Low sucrose levels promote extensive Streptococcus mutans-induced dental caries.

One-tenth percent sucrose significantly promotes dental caries induced by Streptococcus mutans in young gnotobiotic rats. Maximum caries activity was observed in rats provided a purified diet containing 3% sucrose.

Sucrose- and Fructose-Specific Effects on the Transcriptome of Streptococcus mutans, as Determined by RNA Sequencing.

Recent genome-scale studies have begun to establish the scope and magnitude of the impacts of carbohydrate source and availability on the regulation of gene expression in bacteria. The effects of sugars on gene expression are particularly profound in a group of lactic acid bacteria that rely almost entirely on their saccharolytic activities for energy production and growth. For Streptococcus mu...

Effect of pH upon sucrose and glucose catabolism by the various genogroups of Streptococcus mutans.

Sucrose and glucose catabolism by seven strains of Streptococcus mutans belonging to six serotypes was assayed at pH's 6.5, 5.0, 4.5, and 4.0 with a radioisotopic tracer assay. The strains differed in their patterns of metabolic stimulation and inhibition at the different pH levels, falling into groups corresponding to the genetic groups described by Coykendall. The genogroup I (serotypes c and...